Evaluation of antiarthritic activity of Strychnos potatorum Linn seeds in Freund's adjuvant induced arthritic rat model

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Evaluation of antiarthritic activity of Strychnos potatorum Linn seeds in Freund's adjuvant induced arthritic rat model

BACKGROUND Strychnos potatorum Linn (Loganiaceae) is a moderate sized tree found in southern and central parts of India, Sri Lanka and Burma. In traditional system of medicine, Strychnos potatorum Linn seeds were used for various ailments including inflammation, diabetes etc. To investigate the folkloric use of the seeds the present study was carried out on Freund's adjuvant induced arthritic r...

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Antidiabetic effect of seeds of Strychnos potatorum Linn. in a streptozotocin-induced model of diabetes.

The antidiabetic effect of seeds of Strychnos potatorum Linn. was evaluated in a model of diabetes mellitus using streptozotocin (40 mg/kg b.w., i.p.). Changes in fasting blood sugar were estimated periodically for 12 weeks along with weekly measurement of body weight, food and water intake for 4 weeks. The antidiabetic effects were compared with glipizide as the reference hypoglycemic drug. St...

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Pharmacognostic and Phytochemical Investigations in Strychnos potatorum Linn . F .

Objective: To investigate the pharmacognostic and preliminary phytochemical characteristics of leaves of an endangered medicinally important forest tree species Strychnos potatorum. Methods: Pharmacognostic and phytochemical investigations were conducted in terms of macroscopic, microscopic, physicochemical and preliminary phytochemical parameters. Results: The macro and microscopic study revea...

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anti-arthritic activity of premna serratifolia linn., wood against adjuvant induced arthritis

adjuvant induced arthritis is a chronic crippling, skeleton-muscular disorder having nearest approximation to human rheumatoid arthritis for which there is currently no medicine available effecting a permanent cure. even modern drugs used for the amelioration of the symptoms, offer only temporary relief and also produce severe side effects. in the indigenous system of medicine, wood of premna s...

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Anti-arthritic Effect of 1'-acetoxychavicol Acetate in Complete Freunds Adjuvant-induced Arthritis in Rats

1'-Acetoxychavicol acetate (ACA) is a phenylpropanoid present in Alpinia galanga (L) Willd syn. Languas galanga. The objective of this study was to isolate 1'-Acetoxychavicol acetate (ACA) from acetone extract of Alpinia galanga (AEAG) and evaluate anti-arthritic activity of 1'-Acetoxychavicol acetate (ACA) and acetone extract of Alpinia galanga (AEAG) on complete Freund’s Adjuvant-induced arth...

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ژورنال

عنوان ژورنال: BMC Complementary and Alternative Medicine

سال: 2010

ISSN: 1472-6882

DOI: 10.1186/1472-6882-10-56